References and Sources

Updated September 29, 2026

The research notes on this site draw on the sources below. Study details are summarized in our own words. We did not find a published trial of Retina Clear itself.

1. AREDS Research Group. A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8. Archives of Ophthalmology, 2001;119(10):1417-1436.
2. AREDS2 Research Group. Lutein + zeaxanthin and omega-3 fatty acids for age-related macular degeneration: the Age-Related Eye Disease Study 2 (AREDS2) randomized clinical trial. JAMA, 2013;309(19):2005-2015.
3. Canter PH, Ernst E. Anthocyanosides of Vaccinium myrtillus (bilberry) for night vision: a systematic review of placebo-controlled trials. Survey of Ophthalmology, 2004;49(1):38-50.
4. Falsini B, et al. Influence of saffron supplementation on retinal flicker sensitivity in early age-related macular degeneration. Investigative Ophthalmology & Visual Science, 2010;51(12):6118-6124.
5. National Institutes of Health, Office of Dietary Supplements. Vitamin A, Vitamin C, Vitamin E, Zinc, Selenium and Copper fact sheets for health professionals. https://ods.od.nih.gov/factsheets/list-all/
6. National Center for Complementary and Integrative Health. Ginkgo: safety and evidence summary. https://www.nccih.nih.gov/health/ginkgo
7. National Eye Institute. Age-related macular degeneration and AREDS/AREDS2 patient information. https://www.nei.nih.gov/
8. American Academy of Ophthalmology. Eye health patient guidance on digital eye strain and routine eye exams. https://www.aao.org/eye-health
9. U.S. Food and Drug Administration. Dietary supplements: what the FDA does and does not review before sale. https://www.fda.gov/food/dietary-supplements